A research team from the Medical University of Vienna has made further progress in the treatment of intestinal inflammation.
Jude Phillip, assistant professor in the Department of Biomedical Engineering, received an R35 MIRA award from the National Institutes of Health.
He studies how tumor-recognizing T cells — a type of immune cell — respond to these solid tumors, and how to improve those responses to help patients. One research focus is on CD4, or "helper" T cells ...
More information: Ganesan Ramamoorthi et al, Antitumor CD4+ T helper 1 cells target and control the outgrowth of disseminated cancer cells, Cancer Immunology Research (2025). DOI: 10.1158/2326 ...
Panel E shows the flow cytometric analysis of peripheral blood on day 162. Panel F shows the CAR+CD4−CD8− T-cell counts in peripheral blood (blue line) and bone marrow (purple stars ...
The same team of scientists also showed that KROS 101 increased the proliferation of helper and cytotoxic T cells (CD4+ and CD8+), while decreasing T reg cell growth in a melanoma model.
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