T-cell therapy, originally developed for haematological malignancies, has recently emerged as a promising therapy for ...

Chimeric antigen receptor-T (CAR-T) cell therapy, initially successful in hematologic malignancies, presents a promising avenue for treating solid tumors, including CRC. This review explores the ...

Some of those patients will experience refractory cancer – cancer that does not respond to initial treatment or becomes ...

have developed a way to add features to T cells to help them overcome mechanisms of chimeric antigen receptor (CAR) T cell therapy resistance. Their new system is outlined in a paper published ...

For example, chimeric antigen receptor (CAR) T cell therapies work ... The application of single-cell multiomics to simultaneously capture increasingly rich datasets from T cell populations ...

Confounding factors with respect to specifications for toxicity and potentially lethal side effects in chimeric antigen receptor (CAR ... on the chip are used to capture and isolate single ...