Therefore, chromatin is further coiled into an even ... the DNA becomes highly compacted into the classic metaphase chromosomes that can be seen with a light microscope. Once a cell has divided ...

The improper segregation of chromosomes during cell division leads to abnormalities that disrupt the proper functioning of ...

Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...

Thus, in the reconstruction of the four daughter nuclei, two of them contain more chromatin than the other two. The resulting pollen grains, however, look alike. 14. In the somatic mitosis there are ...

We are interested in the mechanism of chromosome replication, a process that is highly conserved across eukaryotes and that involves the duplication of both the chromosomal DNA and its associated ...

The largest of these loops results from the helical coiling of chromatin (the thick line in this illustration). This coiling causes the chromosome to resemble a spring. Chromatin refers to ...

Chromatin is the physiological state of the genome. Approximately 50% of chromosomes and chromatin is protein. These include histones, transcription factors, nuclear receptors, co-activators, ...

Eventually, the chromosome loses its original structure and genetic information to the ravages ... “We proposed that dehydration led to a glass transition of chromatin that arrested molecular movement ...

each chromosome occupies its own specific region in the nucleus. "If we look at the average chromatin structures in human cells and many other organisms, we will see that chromosomes seem to be ...

View Full Profile. Learn about our Editorial Policies. Lis and Gilmour focused on identifying proteins that bound to specific chromatin sites to understand the mechanisms of gene regulation. To do so, ...