How is all of that DNA packaged so tightly into chromosomes and squeezed into ... The basic repeating structural (and functional) unit of chromatin is the nucleosome, which contains eight histone ...

However, the development of technologies such as chromosome conformation capture (3C) has led to a better characterization of long-range chromatin interactions, and several studies support the ...

To elucidate the effect of chromosomal inversions on the epigenetic state of chromatin and the activity of genes, the research team used CRISPR/Cas-based chromosome engineering to generate ...