Afterward, you'll wear a bandage over the injection site. Are cortisone shots painful? You might feel some pain when the needle is inserted, but people often report feeling more pressure than pain.

Cortisone shots are commonly used to treat joint-related problems like arthritis, tendonitis, and bursitis. Cortisone shots can provide long-term pain relief by decreasing inflammation in joint ...

You can think of the cortisone shot as a bottle of ibuprofen that's squirted into the knee joint through a needle. Relief from a cortisone shot varies. It varies depending on the diagnosis.