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Discoidin 结构域受体抑制剂 DDR1-IN-1:开启恶性外周神经鞘膜瘤治疗新征程
研究人员针对恶性外周神经鞘膜瘤(MPNST),探究阻断胶原蛋白与受体相互作用的影响,发现 DDR1-IN-1 可诱导其细胞死亡,为治疗提供新策略。 恶性外周神经鞘膜瘤(MPNST),听起来或许有些陌生,但它却是一种相当棘手的软组织肉瘤。大约一半的 MPNST 与 1 型 ...
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