The selective advantage for the establishment and, more interestingly, the maintenance of heterogeneity in tumors is unclear. Our results indicate that tumors benefit collectively from protecting ...

Gastrointestinal (GI) cancers account for 26% of the global cancer incidence and 35% of all cancer-related deaths. Although the top 5 cancers in this group ...

The Tammela lab is interested in understanding the remarkable phenotypic heterogeneity of cancer cells within tumors. We approach this question using a combination of sophisticated genetically ...

To extensively investigate the cellular and molecular heterogeneity of CC, particularly ADC ... This study was supervised and approved by the Ethics Committee Board of Hunan Cancer Hospital. The ...

Their data show how genetic and non-genetic factors determine the functional heterogeneity of blood cancer cells and reveal new therapeutic targets. In particular, under the selection pressure of ...

TrialTranslator uses machine learning to assess cancer RCT generalizability, revealing survival gaps for high-risk patients and enhancing research accuracy.

Gastric cancer remains a critical public health issue globally, with new statistics from the National Cancer Center indicating about 514,000 new cases in ...

To fully understand cancer, researchers must use methods that allow them to fully appreciate heterogeneity within tumors and across the tumor microenvironment. New computational and omics technologies ...

The drug response and prognosis of cancer patients may be strongly dependent on specific cancer subclones e.g cancer heterogeneity, as well as on the diversity and interactions of multiple cell types ...