More information: David Dansu et al, Histone H4 acetylation differentially modulates proliferation in adult oligodendrocyte ...

which paralleled acetylation of K9 and K14, while transcriptionally inactive chromatin was associated with K9 methylation. While this study supports the existence of gene regulation by a histone ...

“HDACi increases histone acetylation, which in turn modulates the expression of genes that counteract proliferation of pulmonary arterial smooth muscle and endothelial cells, endothelial ...

For instance, histone acetylation reduces the positive charge of the histone proteins, thereby reducing their affinity for DNA and causing the chromatin to open (Figure 2). This in turn permits ...

Cancer cells are known to favor aerobic glycolysis for energy production, a phenomenon termed the Warburg effect.

A new review highlights the pivotal role of LSD1 (lysine-specific demethylase 1) in regulating critical cellular processes ...

PDHX acetylation promotes tumor progression by disrupting PDC assembly and activating lactylation-mediated gene expression.