Studies in numerous HD models have shown that mutant huntingtin alters histone acetyltransferase activity, and indicate that aberrant activity of this enzyme might be an underlying mechanism of ...
Shanghai Henlius Biologics Co. Ltd. has synthesized histone acetyltransferase KAT6A (monocytic leukemia zinc finger protein; MOZ; MYST-3) and/or histone acetyltransferase KAT6B (MOZ2; MYST-4) ...
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Repressed but ready to go: How bivalency holds developmental genes in a poised state for expressionOne of these proteins is the histone acetyltransferase complex KAT6B (MORF), identifying this for the first time as a reader of bivalent nucleosomes and regulator of bivalent gene expression ...
The other fusion partners involved are CBP and TIF2, both of which are known transcriptional coactivators with intrinsic histone acetyltransferase activity. We have cloned MORF, a new human ...
Researchers from Shenzhen University have evaluated the potential antiallergic effects of the histone acetyltransferase KAT6A inhibitor WM-1119 on IgE-mediated mast cell activation and allergic ...
1.*Ikeda, T., Uno, M., Honjoh, S. & Nishida, E.: "The MYST family histone acetyltransferase complex regulates stress resistance and longevity through transcriptional control of DAF-16/FOXO ...
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