“I asked my supervisor, ‘What are those proteins down there?’ he recalls. “And he said, ‘Well, they’re histone molecules. We have no clue what they’re doing. They sit in the nucleus and do something ...
In histone lactylation, incompletely metabolized lactate produces by-products that attach molecules called lactyl groups to ...
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A newly discovered biomarker can predict cancer aggressivenessHistone RNA is unique in that its structure prevents the RNA molecules from being detected by current methods. Thus, the expression of histone genes may be significantly underestimated in tumor ...
Histone RNA is unique in that its structure prevents the RNA molecules from being detected by current methods. Thus, the expression of histone genes may be significantly underestimated in tumor ...
These attendant proteins bind to histones and nucleosomal DNA, and their binding to these molecules is affected by the histone modification state. The modification state helps determine whether ...
Scientists have discovered a previously unknown mechanism for how aggressive brain cancers reprogram immune system cells from fighting cancer to enabling further tumor growth.
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