(a) In the 'classical' pathway, multiple pyramidal cells (for simplicity, only one pyramidal cell is shown: P 1) excite the inhibitory interneuron (I) at its soma. The interneuron then inhibits P ...

We conclude that the amplitude coupling of CA1 ripple oscillations is higher within than between hemispheres and tends to decline with shank distance. Nevertheless, our results demonstrate generally ...

The biological roots of Tourette disorder occur in the basal ganglia, structures deep in the brain involved in the control of ...

By analyzing about 12,000 transcriptomic single-cell nuclear data, the researchers were able to create a comprehensive molecular atlas of hippocampal interneurons and identify 15 interneuron subtypes.

cohorts of the Company’s ongoing open-label Phase 1/2 clinical trial of NRTX-1001 GABAergic interneuron cell therapy in adults with drug-resistant, unilateral MTLE. The low-dose cohort ...

In December at the American Epilepsy Society's Annual Meeting, Neurona Therapeutics presented updated data from both the low-dose (n=5) and high-dose (n=5) cohorts of the Company's ongoing open-label ...