A recent study showed that paracrine delivery of miR-21a-5p by bone marrow mesenchymal stem cells-derived apoptotic bodies ...

1 There are three different macrophage types, naïve (M0), antitumor (M1), and protumor (M2). M1 macrophages accumulate at the tumor and exert antitumor activity. Researchers have attempted to use them ...

To overcome these hurdles, Carisma has developed CAR-M, leveraging the natural role of macrophages to ... can be directed to develop an M2, immunosuppressant phenotype that holds promise for ...

Another advance by Dr. Spiller's lab is the proof-of-concept that biomarkers based on macrophage phenotype can be used to predict healing outcome of human diabetic foot ulcers, a major unmet clinical ...