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Nature Medicine | 治疗朊病毒疾病:基因编辑带来的曙光
引言朊病毒疾病(Prion Disease)是一种罕见但致命的神经退行性疾病,其特征是由于朊病毒蛋白(Prion Protein, PrP)的异常折叠,导致神经细胞损伤和脑功能的逐步衰退。尽管这种疾病包括多种亚型,例如克雅氏病(Creutzfeldt ...
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