为解决败血症相关肺纤维化（PF）治疗难题，上海交通大学医学院附属仁济医院研究人员探究 PKM2 对 AECs 线粒体动力学和 EMT 的调控。结果发现 PKM2 是关键调节因子，抑制它可缓解 PF。推荐一读，或为相关研究带来新思路。 在医学领域，急性呼吸窘迫综合征（ARDS ...

上海中医药大学附属岳阳中西医结合医院的研究人员在《Cell Death and Disease》期刊上发表了题为 “The RNA M5C methyltransferase NSUN2 promotes progression of hepatocellular carcinoma by enhancing PKM2-mediated glycolysis” 的论文。该研究意义重大，揭示了 ...

A pivotal role of P21-activated kinase 5 (PAK5) in endometriosis progression has been uncovered, revealing that PAK5-mediated phosphorylation of pyruvate kinase M2 (PKM2) is critical for anaerobic ...