At endosomes, these proteins are either recycled back to the plasma membrane or are sorted for degradation. The recycling of plasma membrane proteins mostly occurs at early and recycling endosomes ...
Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ...