Promoter sequences are DNA sequences that define where transcription of a gene by RNA polymerase begins. Promoter sequences are typically located directly upstream or at the 5' end of the ...

In addition, regulatory sites on prokaryotic DNA are typically located close to transcription promoter sites — and this plays an important part in gene expression. For an example of how this ...

Chinese scientists have uncovered two major genes responsible for sorghum's double-grain spikelet that dramatically enhance ...

in New York describe a bioinformatic strategy to predict gene promoters and first exons (Nat Genet 2001, DOI: 10.1038/ng780).They developed a new program, called FirstEF, that attempts to predict the ...

The numbers of the principal regulatory elements present in insulin promoters are listed. Given the complexity and uncertainty of predicting the transcriptional outcome of mutations within ...

Genes also contain regulatory sequences, such as promoters and enhancers, which control when and where the gene is expressed. These sequences interact with transcription factors and other regulatory ...

New analyses find that divergent transcription, in which one promoter directs the expression of two adjacent genes oriented in opposite directions, is conserved across all domains of life. Jack is a ...

Legendary KISS bassist Gene Simmons is giving fans the chance to live out their dreams of rock stardom by letting them be his roadie for a day – but it comes with a hefty price tag. In 2024, Gene ...

On track to declare two in vivo editing development candidates via gene upregulation, one in HSCs and one in liver, in mid-2025Company to present further in vivo HSC preclinical data and further in ...

It is essential that new human ß-cell lines be developed and widely distributed in order that physiologically and medically relevant studies on the human insulin promoter can be carried out.