T cell engagers are designed to redirect immune effector cells against cancer cells by simultaneously binding to a specific tumor-associated antigen expressed on the cancer cells and the T cell ...

In doing so, the bispecifics redirect T cells of any specificity to target cells. ImmTAX molecules have inherent advantages over other modalities. The molecules recognize peptides derived from ...

Typically, TriAx antibodies target tumor-associated antigens and engage T cell receptors to redirect T cell cytotoxicity. These heterodimeric antibodies are designed primarily for the generation ...

In some instances of rhabdomyosarcoma, a rare cancer arising from muscle cells stalled in their journey toward their final non-dividing state, mutations to MyoD’s DNA-binding region redirect the ...

EpimAb_LogoPlanegg/Martinsried and Shanghai, February 27, 2025. Medigene AG (Medigene, FSE: MDG1, Prime Standard) and EpimAb Biotherapeutics, ...