*仅供医学专业人士阅读参考我们知道,β-淀粉样蛋白(Aβ)沉积导致的淀粉样斑块,以及tau蛋白过度磷酸化导致的神经纤维缠结,是阿尔茨海默病(AD)的两个典型病理特征。近年来,尽管有不少研究显示,Aβ沉积是AD发病的起点,会触发tau蛋白的聚集和传播, ...
虽然人类研究显示,tau 和淀粉样相关的神经回路功能障碍在 AD 患者的记忆障碍中存在分离效应和相互作用,但 Aβ 和 tau 如何相互作用导致认知和神经精神症状仍不清楚。此外,Aβ 和 tau 导致突触功能障碍以及情感和记忆神经回路易损性的神经病理相互作用机制也尚未明确。
A new study showed that people who took longer to enter this dream phase of sleep had higher levels of amyloid beta and tau, ...
In obesity, Lilly removed a dual amylin calcitonin receptor agonist (DACRA) from its phase 1 pipeline. Lilly got into DACRAs ...
For each structural strain of tau fibrils, they identified amino acids without which the strain cannot form its signature ...
Feraud Director of the Center for Alzheimer’s Disease Research, wins the 2025 Rainwater Prize for Innovative Early-Career ...
JERUSALEM, Jan. 27, 2025 (GLOBE NEWSWIRE) -- Alpha Tau Medical Ltd. ("Alpha Tau", or the “Company”) (NASDAQ: DRTS, DRTSW), the developer of the innovative alpha-radiation cancer therapy Alpha ...