One avenue for new vaccine development is mucosal vaccines. In theory, dosing the vaccine directly into the respiratory tract ...

A research team from the Medical University of Vienna has made further progress in the treatment of intestinal inflammation.

More information: Ganesan Ramamoorthi et al, Antitumor CD4+ T helper 1 cells target and control the outgrowth of disseminated cancer cells, Cancer Immunology Research (2025). DOI: 10.1158/2326 ...

Jude Phillip, assistant professor in the Department of Biomedical Engineering, received an R35 MIRA award from the National Institutes of Health.

Balancing the immune system is a delicate act. If it’s too weak, infections and cancer can take hold; if it’s too strong, autoimmune diseases or transplant rejection can occur. Researchers have ...

He studies how tumor-recognizing T cells — a type of immune cell — respond to these solid tumors, and how to improve those responses to help patients. One research focus is on CD4, or "helper" T cells ...

Panel E shows the flow cytometric analysis of peripheral blood on day 162. Panel F shows the CAR+CD4−CD8− T-cell counts in peripheral blood (blue line) and bone marrow (purple stars ...

The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...