Researchers at the University of Colorado Anschutz Medical Campus have successfully developed a supercharged iteration of CAR-T cell therapy that can enhance the effectiveness and longevity of the ...

The cancer microenvironment ... A study now describes a cell-autonomous, motile, organelle-rich extracellular vesicle with cell-like functions and the largest one yet — the blebbisome.

Mar. 12, 2025 — Metastatic melanoma is the most aggressive form of skin cancer. In an effort to achieve targeted therapy for metastatic melanoma, researchers recently developed a new radioactive ...

Microbes, traditionally thought to lack organelles, get a metabolic boost from geometric compartments that act as cauldrons for chemical reactions. Bioengineers are eager to harness the compartments ...

Mitochondria are cytoplasmic organelles found in most eukaryotic ... Bid (tBid), while increased VDAC2 and Bak in liver cancer cells allow specific targeting by combinations of tBid activators ...

This paper presents the important finding that BNIP3/NIX, a mitophagy receptor, and its binding to ATG18 are required for mitophagy during muscle cell reorganization in Drosophila. Although the ...

Mar. 10, 2025 — Feral cats have long been suspects in killing native species reintroduced into Australian conservation areas. DNA testing of the carcasses puts ...

Metabolic dysfunction-associated steatohepatitis (MASH) is a liver disease that progresses without symptoms and is associated ...

Polyphosphate (polyP) exists in all life forms; however, its biological functions in metazoans are understudied. Here, we explored Drosophila as the first genetic model to explore polyP biology in ...

Head in the clouds? Use the moon’s clash with Jupiter to dive down dreamy rabbit holes! Imagination is your best asset today. Chase down curiosities. On the way, you’ll pick up on the new ...

As a postdoc, he focused on the molecular characterization of cancer and hematopoietic stem cells with Andreas Trumpp at the DKFZ and Jeroen Krijgsveld at EMBL. Daniel joined The EMBO Journal in 2015.