The basic repeating structural (and functional) unit of chromatin is the nucleosome, which contains eight histone proteins and about 146 base pairs of DNA (Van Holde, 1988; Wolffe, 1999).

While aging-related PTMs caused significant local changes to the proteins, the overall structure and integrity of chromatin remained intact. However, enzymes that typically interact with chromatin ...

Despite extreme local changes to the protein brought by aging-related PTMs, the overall structure and integrity of chromatin seemed unaffected. However, enzymes that typically interact with it ...

A study reveals cannabis and tobacco use harm sperm quality and DNA integrity, with cannabis causing greater damage, raising ...