Chimeric antigen receptor-T (CAR-T) cell therapy, initially successful in hematologic malignancies, presents a promising avenue for treating solid tumors, including CRC. This review explores the ...

Introduction: Circulating tumor cells (CTCs) have attracted significant interest as a biomarker for cancer diagnosis. In this study, we judiciously constructed a recombinant MUC1-dependent adenovirus ...

Researchers from Iwate Medical University and Tohoku University have revealed that it is possible to predict cancer relapse and treatment response by measuring circulating tumor DNA (ctDNA), in ...

to target a cell-surface receptor called DR5 (death receptor 5) that many tumor cells have. When activated, DR5 can trigger the death of these cells by a self-destruct process called apoptosis.

Circulating tumor cells (CTC) are the leukemic phase of solid tumors and are essential for the establishment of distant metastasis for a given cancer. To be successful in establishing metastasis ...

to optimize next-generation induced pluripotent stem cell (iPSC)-derived cancer cell therapies. This collaboration underscores Ginkgo’s capacity to deploy high-throughput biological approaches to ...

iPSC-derived cell therapies have the potential to transform cancer care by offering scalable, 'off-the-shelf' treatment options. However, bringing efficacious therapies to patients requires robust ...

Get Instant Summarized Text (Gist) Research has uncovered why tumor cells die differently after radiotherapy, revealing that DNA repair pathways dictate the mode of cell death. When homologous ...

Scientists at Children's Medical Research Institute (CMRI) have solved a big mystery in cancer research – why cells die in different ways following radiotherapy. This surprising finding opens up ...

Collaboration leverages Ginkgo's cell engineering and screening platform to enhance the potency and persistence of Universal Cells' iPSC-derived immune cell therapeutics BOSTON, Jan. 13, 2025 ...

We also thank Laurene Kelly for English revision of the manuscript. The work on circulating tumor cells performed by the authors was partly supported by a research grant from the Foundation IRCCS ...