Hosted on MSN25d
Therapeutic approach to treat virus-induced lung failure for severe COVID-19 shows promise in clinical trial
A new clinical study shows that an inhibitor of Fas ligand (FasL), also called CD95 ligand (CD95L), led to a faster recovery of COVID-19 patients and reduced mortality. On average, it took eight ...
Nature3mon
Not so Fas: Re-evaluating the mechanisms of immune privilege and tumor escape
The original idea was logical. FasL expressed on tissues would engage the Fas receptor expressed on the surfaces of immune cells, causing them to undergo programmed cell death ().The idea that ...
Hosted on MSN26d
FasL inhibitor speeds recovery and reduces mortality in severe COVID-19 patients
A new clinical study shows that an inhibitor of Fas ligand (FasL), also called CD95 ligand (CD95L), led to a faster recovery of COVID-19 patients and reduced mortality. On average, it took eight ...
Nature28d
Fas counter-attack–the best form of tumor defense?
FasL-negative, subcutaneous AK-5 tumors showed ... O'Sullivan, G.C., Collins, J.K. & Shanahan, F. The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand.