A miRNA multi-omics study reveals not only mechanisms for miRNA dysregulation, but also the tumor heterogeneity and ... nucleatum in colorectal cancer cells and provides clues to malignant ...
To create one of the most advanced immunotherapies in cancer, CAR-T cell therapies, scientists engineer immune T cells to carry a synthetic protein on their surfaces. This protein, called the ...
Intratumor heterogeneity (ITH) is associated with tumor progression ... Methods: We obtained clinical information and gene expression data for COAD patients from The Cancer Genome Atlas (TCGA) ...
Alterations in the expression and activity of specific translation factors, and the uncoupling of translational regulation from inhibition by tumour cell stresses, such as hypoxia and nutrient ...
Researchers investigated immune-related adverse effects and characteristics that may predict their incidence in patients receiving ICIs for gastrointestinal cancers.