Shanghai Henlius Biologics Co. Ltd. has synthesized histone acetyltransferase KAT6A (monocytic leukemia zinc finger protein; MOZ; MYST-3) and/or histone acetyltransferase KAT6B (MOZ2; MYST-4) ...

实验表明，该位点的竞争拮抗作用会减弱 KAT7 的组蛋白乙酰转移酶（Histone Acetyltransferase，HAT）活性，影响其对底物 H3K14 和 H4K5/8/12 的乙酰化水平。 hMOF 是 DNA 损伤刺激下 KAT7 的主要巴豆酰基转移酶：研究人员通过一系列实验，包括转染不同的组蛋白巴豆酰基转移 ...

Enzyme mechanisms are the chemical transformations, and the steps within them, generated by enzymatic action on substrates. The mechanism of enzyme catalysis is similar in principle to other types ...

Mass spectrometry is an analytical technique that uses an instrument called a mass spectrometer to measure the mass-to-charge ratios of molecular ions. Molecules fragment within the mass ...