For instance, lysine residue (K) can be targeted for distinct modifications such as acetylation, methylation, ubiquitination, or sumoylation and can harbor one, two, or three methyl residues. Moreover ...

Histone modifications have been shown to play a role in chromatin packing and ... H3K4 can be methylated by methyltransferase, Set1A, and demethylated by JARID1A, a demethylase. Methylation of lysine ...

A new review highlights the pivotal role of LSD1 (lysine-specific demethylase 1) in regulating critical cellular processes ...

These useful findings assigned a novel functional implication of histone acylation, crotonylation. Although the mechanistic insights have been provided in great detail regarding the role of the YEATS2 ...

Department of Physics, Chemistry and Pharmacy, University of Southern Denmark, Campusvej 55, 5230 Odense, Denmark ...

State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong 999077, China Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, The University of ...