Monoamines, basic nitrogenous molecules containing one amine group ... Histamine, like serotonin and dopamine, is involved in histone monoaminylation. The Maze group recently described H3 ...

Post-translational modifications of DNA and histones are epigenetic mechanisms, which affect the chromatin structure, ultimately leading to gene expression changes. A number of different epigenetic ...

In histone lactylation, incompletely metabolized lactate produces by-products that attach molecules called lactyl groups to ...

It can coil, bend, or even break. Certain molecules can bind to it, making some regions inaccessible. The recent study emerging through the collaboration of Hungarian laboratories and their foreign ...

Scientists have discovered a previously unknown mechanism for how aggressive brain cancers reprogram immune system cells from fighting cancer to enabling further tumor growth.

Researchers at Fred Hutch Cancer Center have discovered an overlooked mechanism driving aggressive breast and brain tumors ...

Histone RNA is unique in that its structure prevents the RNA molecules from being detected by current methods. Thus, the expression of histone genes may be significantly underestimated in tumor ...