Using conventional cell models to study histone modifications has been the ... It was not until 2019 that pioneering studies identified molecules that are typically considered to be chemical ...
As the state of the cell changes, it seems that the chromosome structure also changes, while influencing gene expression. Further, the chromosome structure is affected by a foam-like cloud of histone ...
In the late 1970s, when Hans Reul was a student running gels on the rich soup of proteins around DNA and RNA, he found himself wondering about the function of those nongenetic molecules in his samples ...