A Prescription Drug User Fee Act target date of December 12, 2025 has been set for the application. The Food and Drug Administration (FDA) has accepted for review the Biologics License Application ...

LIB Therapeutics announced that the US Food and Drug Administration (FDA) has accepted the Biologics License Application (BLA) for lerodalcibep, a treatment aimed at lowering low-density ...

Lerodalcibep could be a key treatment option for patients needing additional LDL-C reduction beyond existing therapies. Credit: Katernya Kon via Shutterstock. LIB Therapeutics announced that the US ...

Mechanism of action describes the process by which a molecule, such as a drug, functions to produce a pharmacological effect. A drug’s mechanism of action may refer to its effects on a ...

Enzyme mechanisms are the chemical transformations, and the steps within them, generated by enzymatic action on substrates. The mechanism of enzyme catalysis is similar in principle to other types ...

Despite much research, the exact molecular mechanism underlying stator function is yet unclear. In a new study, researchers analyzed the flagellar motor in Vibrio alginolyticus using cryo-electron ...

In this review, we discuss some of the recent findings regarding less-known molecules and new functions of well-known molecules. Understanding the mechanisms of these molecules in macrophages has the ...

State Key Laboratory of Heavy Oil Processing, College of Chemistry and Chemical Engineering, China University of Petroleum (East China), Qingdao 266580, China ...

A multifactorial approach should be used to account for all the factors involved-that is, the internal and external risk factors as well as the inciting event (the injury mechanism). Although such ...

Findings from the phase 1b Beamion LUNG-1 trial showed an objective response rate of 71% in NSCLC patients treated with zongertinib. The Food and Drug Administration (FDA) has granted Priority ...