called CAR T-cells, has kept a person free of a potentially fatal nerve tumour for a record-breaking 18 years. “This is, to my knowledge, the longest-lasting complete remission in a patient who ...

In mice, blocking nerve function inhibited cancer growth and increased the sensitivity of tumor cells to certain chemotherapies and immunotherapies. For several years, scientists have been ...

However, the precise mechanism of such CNS-related toxicities remains elusive. Methods: The effect of entrectinib-induced nerve cell damage was evaluated by the nerve cells (PC12, HT22 and SK-N-SH) ...

In a study published in Nature Communications, the researchers have discovered a new type of brain cell that plays a central role in our ability to remember and recognize objects. Called "ovoid ...

Here we show that the cell–cell interaction molecule, N-cadherin, regulates both adhesion and repulsion processes during Schwann cell (SC) collective migration, which is required for peripheral nerve ...

barrier-forming cells of the perineurium surrounding and protecting nerve fascicles, and connective tissue-resident cells within the intra-fascicular endoneurium and inter-fascicular epineurium. We ...

Isolated retinas from these eyeballs were labeled ... cells and microglia. In conclusion, our study shows an important role of A2 expression in mediating ONC pathology. A2 deletion ameliorates RGC ...