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Cancer-independent somatic mutation of the wild-type NF1 allele in normal tissues in neurofibromatosis type 1. Nature Genetics , 2025; DOI: 10.1038/s41588-025-02097-2 Cite This Page : ...

Despite what was previously thought, new research has shown that genetic changes alone cannot explain why and where tumors grow in those with the genetic condition neurofibromatosis type 1 (NF-1).

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Sumrall, MD The FDA has approved an oral, small molecule MEK inhibitor for adult and pediatric patients 2 years of age and older with neurofibromatosis type 1 who have symptomatic plexiform ...