Edible cannabis containing 50 mg or more of THC has been linked with serious side effects. Regularly taking large amounts of cannabis might cause cannabinoid hyperemesis syndrome (CHS).

Dosing ranges from 15 to 30 mg every 6 to 8 hours. The drug has strong anticholinergic side effects. Although it was available before oxybutynin, it has one of the highest side effect profiles.

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