Chromatin is a flexibly joined chain of nucleosomes that exists inside ... mouse stem cell renewal and sperm production through a three-dimensional interacting chromatin network that maintains ...

Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...

The human brain houses a complex network of cells that communicate and interact in intricate ways. Within each of these cells lies a dynamic interplay of genetic components, including chromatin ...

Dr. Toshio “Toshi” Tsukiyama studies how cells regulate chromatin, the packaging proteins responsible for compressing several feet of DNA inside each cell’s tiny nucleus. This genetic material needs ...