Cell morphology heterogeneity in epithelial tissues, driven by asymmetric cell division, correlates with nucleus morphology and impacts chromatin state diversity through histone modifications.

Chromatin is one of the most complex materials in cells and enables the massive amount of DNA in the genome to fold up and fit into the nucleus of each cell. The building blocks of this genetic ...

Spatial organization of chromatin plays a critical role in genome regulation. Previously, various types of affinity mediators and enzymes have been attributed to regulate spatial organization of ...