Therefore, chromatin is further coiled into an even ... the DNA becomes highly compacted into the classic metaphase chromosomes that can be seen with a light microscope. Once a cell has divided ...

Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...

Together, these bead-like structures form chromatin fibres that fold up tightly into chromosomes. Folded chromatin structures are not random, however. They are determined by the genetic code and, in ...

The improper segregation of chromosomes during cell division leads to abnormalities that disrupt the proper functioning of ...

Strikingly, a Mb long inactive artificial bacterial chromosome was able to bind plasmid molecules from their native binding positions, illustrating how the plasmid is spontaneously attracted by ...

Chromosomes and Gene Expression eLife reviews research ranging from transcription and RNA processing to epigenetics and chromatin biology. Learn more about what we review and sign up for the latest ...

SEATTLE--(BUSINESS WIRE)--Parse Biosciences, the leader in accessible and scalable single cell sequencing, today affirmed their plans to proceed with development and future release of their Evercode™ ...

1Department of Nephrology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, China. 4Department of Urology, Shanghai ...

Scientists discovered a way to block hepatitis B infection using an anticancer drug, offering hope for new treatments.