The Greenland shark, a slow-moving giant of the North Atlantic and Arctic Oceans, holds the record as the longest-lived ...

Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...

The improper segregation of chromosomes during cell division leads to abnormalities that disrupt the proper functioning of ...

Scientists discovered a way to block hepatitis B infection using an anticancer drug, offering hope for new treatments.

They are formed in a woman's body before birth and have to be on standby for decades to possibly be fertilized one day. But ...

Chromatin structure describes the physical structure of chromatin within the eukaryotic nucleus and how structure affects chromatin processes such as transcription. The repeating unit of chromatin ...

Strikingly, a Mb long inactive artificial bacterial chromosome was able to bind plasmid molecules from their native binding positions, illustrating how the plasmid is spontaneously attracted by ...

Yeast also has the same way of organizing chromosomes, while in humans and other mammals, each chromosome occupies its own specific region in the nucleus. “If we look at the average chromatin ...

It revealed that the HBV X gene, which produces HBx protein, is particularly sensitive to the formation of nucleosomes-the basic units of chromatin, made of histone proteins, which package and ...

each chromosome occupies its own specific region in the nucleus. "If we look at the average chromatin structures in human cells and many other organisms, we will see that chromosomes seem to be ...

Genes are encoded in the DNA that makes up chromosomes, which consist of DNA wrapped around proteins, forming a complex structure called chromatin. To be functional, the genes must be expressed.

Together, these bead-like structures form chromatin fibres that fold up tightly into chromosomes. Folded chromatin structures are not random, however. They are determined by the genetic code and, in ...