Therefore, chromatin is further coiled into an even ... the DNA becomes highly compacted into the classic metaphase chromosomes that can be seen with a light microscope. Once a cell has divided ...

To convert a piece of cloned DNA into a centromere-containing human artificial chromosome (HAC), an array of repeated ... centromeric histone CENP-A into and along neighboring chromatin (2). In turn, ...

During interphase, individual chromosomes are not visible, and the chromatin appears diffuse and unorganized. Recent research suggests, however, that this is an oversimplification and that ...

Artificial chromosomes are essentially miniature versions of real ... [encodes] a whole cascade of enzymes involved in a particular pathway,” says chromatin researcher Gary Karpen of Lawrence Berkeley ...

The improper segregation of chromosomes during cell division leads to abnormalities that disrupt the proper functioning of ...

Thus, in the reconstruction of the four daughter nuclei, two of them contain more chromatin than the other two. The resulting pollen grains, however, look alike. 14. In the somatic mitosis there are ...

We are interested in the mechanism of chromosome replication, a process that is highly conserved across eukaryotes and that involves the duplication of both the chromosomal DNA and its associated ...

each chromosome occupies its own specific region in the nucleus. "If we look at the average chromatin structures in human cells and many other organisms, we will see that chromosomes seem to be ...