and the chromatin appears diffuse and unorganized. Recent research suggests, however, that this is an oversimplification and that chromosomes may actually occupy specific territories within the ...

How is all of that DNA packaged so tightly into chromosomes and squeezed into ... The basic repeating structural (and functional) unit of chromatin is the nucleosome, which contains eight histone ...

To convert a piece of cloned DNA into a centromere-containing human artificial chromosome (HAC), an array of repeated ... centromeric histone CENP-A into and along neighboring chromatin (2). In turn, ...

To elucidate the effect of chromosomal inversions on the epigenetic state of chromatin and the activity of genes, the research team used CRISPR/Cas-based chromosome engineering to generate ...