Organismal lifespan can be extended by genetic manipulation of cellular processes such as histone acetylation, the insulin/IGF-1 (insulin-like growth factor 1) pathway or the p53 system.

Histone acetylation is usually associated with transcriptional activation because the affinity of histone proteins for DNA is reduced and chromatin packaging is relaxed. Histone methylation ...

More information: David Dansu et al, Histone H4 acetylation differentially modulates proliferation in adult oligodendrocyte ...

Cancer cells are known to favor aerobic glycolysis for energy production, a phenomenon termed the Warburg effect.

PDHX acetylation promotes tumor progression by disrupting PDC assembly and activating lactylation-mediated gene expression.

with changes in histone acetylation and methylation found in atherosclerotic tissues. Environmental exposure is a significant theme throughout the review. It discusses how factors such as air ...