These include DNA methyltransferase and histone deacetylase (HDAC) inhibitors. Further candidates, including inhibitors of acetyl-lysine readers (bromodomain-containing proteins), are undergoing ...
coli, demonstrating that it does, in fact, generate 4mC marks that could be detected using specific antibodies. Yushenova further demonstrated that bdelloids possess a histone methyltransferase that ...
A recent study delves into the pivotal role of Setd2, a histone methyltransferase enzyme, in embryonic development within mice. Setd2 is instrumental in the trimethylation of histone H3 lysine 36 ...