脂质筏（LRs）作为细胞膜的重要组织者，在细胞信号传导中发挥关键作用。其富含胆固醇、鞘脂等成分，为多种信号分子提供了特定的微环境，使生化反应更高效、精准。在癌症发展进程中，LRs 参与调控多个关键环节，如细胞增殖、迁移和侵袭等，是极具潜力的抗癌药物靶点。

Explore the role of the extracellular matrix (ECM) in prostate cancer progression and discover natural therapies, including ...

The primary node molecules in the cell signaling network in cancer tissues are maladjusted and mutated in comparison to normal tissues, which promotes the occurrence and progression of cancer.

Fourteen hub genes were identified using the two algorithms. The PPI networks of the hub genes were analyzed using the Cytoscape plugin CytoNCA to obtain two key genes (IL10 and Integrin α5 (ITGA5)).

“This study reveals that deleting a gene called Itgb1 in heart wall cardiomyocytes prevents trabeculae formation. We found that the protein β1 integrin encoded by Itgb1 and its ligands, the ...