Detroit started at the San Francisco 43-yard line and ... the failed fourth down to end the drive. The 49ers continue to score at will on the Lions. After two 9-yard gains to start the drive ...

Trades of Deebo Samuel, releases of Kyle Juszczyk, Talanoa Hufanga, Aaron Banks and others walking. Despite all the chaos of ...

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A stunning second-half comeback from 17 points down saw the San Francisco 49ers end ... goal attempt after Detroit's defense stopped the home side's first drive, and the Lions responded by putting ...

Christian McCaffrey scored two touchdowns and Brock Purdy threw for another score as the San Francisco 49ers rallied to a 34-31 victory over the Detroit Lions in the NFC title game Sunday ...

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Watch all of the highlights from the Detroit Lions' 40-34 Week 17 victory over the San Francisco 49ers. Watch Detroit Lions quarterback Jared Goff connect with San Francisco 49ers fullback Kyle ...

San Francisco 49ers host the Detroit Lions on Monday Night Football to disrupt the Lions' quest for the NFC's No. 1 seed. The San Francisco 49ers and Detroit Lions reignite their rivalry under the ...

The Detroit ... the Lions are being linked to a very intriguing linebacker option. There are quite a few talented linebackers who will hit the market. One of them is San Francisco 49ers star ...

The San Francisco ... Spots: Detroit Lions, Indianapolis Colts," Cameron said. "Greenlaw spent much of this past season getting right after his Achilles injury during the 49ers' run to the ...