In eukaryotes, DNA is tightly wound into a complex called chromatin. Thanks to the process of chromatin remodeling, this complex can be "opened" so that specific genes are expressed. Various ...
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Chromatin fiber's genomic 'memory' governs the building blocks of life, study revealsIn the study, investigators utilized nanoscale imaging and sensing technologies along with modeling techniques developed at Northwestern to individually label and observe chromatin fibers ...
When genes are coiled and compacted into chromatin, they're no longer accessible to transcription factors. So how does the cell know where to uncoil in a process called chromatin remodeling?
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