The basic repeating structural (and functional) unit of chromatin is the nucleosome, which contains eight histone proteins and about 146 base pairs of DNA (Van Holde, 1988; Wolffe, 1999).

Single-cell multiomic analyses reveal known and new genes and pathways involved in the development of germ cells and provide a discovery platform for the scientific community.

Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...

In the study, investigators utilized nanoscale imaging and sensing technologies along with modeling techniques developed at Northwestern to individually label and observe chromatin fibers ...

Published in the Journal of the American Chemical Society, the work by researchers at King's College London and collaborators suggests that chromatin, the mix of DNA and protein that houses each ...