B-cell receptor - Wikipedia
The B-cell receptor (BCR) is a transmembrane protein on the surface of a B cell. A B-cell receptor includes both CD79 and the immunoglobulin . The plasma membrane of a B cell is indicated by the green phospholipids .
Role of B-cell receptors for B-cell development and antigen ...
Signals through the B-cell receptor (BCR) guide and are required for B-cell maturation, survival, and fate decision. Here, we review the role of the BCR during B-cell development, leading to the emergence of B1, marginal zone, and peripheral follicular B cells.
B-Cell Receptor - an overview | ScienceDirect Topics
A B-Cell Receptor (BCR) is a unique receptor found on the surface of normal B cells. It consists of pairs of immunoglobulin heavy (IgH) and light (IgL) chains, which allow the BCR to recognize and bind to a variety of antigens.
B-cell receptor: from resting state to activate - PMC
B-cell activation is triggered by the binding of antigen to the B-cell receptor (BCR). The early molecular events triggered by BCR binding of ligand have been well-characterized both biochemically and using optical microscopy techniques to visualize B-cell activation as it happens.
Study Reveals Detailed Structure of B-Cell Receptor
2022年10月25日 · Researchers at Harvard Medical School and the University of Freiberg in Germany have captured the first, long-awaited snapshots at near-atomic resolution of B-cell receptors — intricate assemblages of proteins protruding from the surface of B cells that detect invaders such as viruses and bacteria and alert the cells to fight.
B-Cell Receptor - an overview | ScienceDirect Topics
The B cell receptor (BCR) covers the surface of mature B cells, and initiates cellular responses that lead to B cell activation and antibody production. Each B cell expresses a unique B cell receptor with specificity for a unique antigen.
The Diversity and Molecular Evolution of B-Cell Receptors ...
B-cell receptors (BCRs) are membrane-bound immunoglobulins that recognize and bind foreign proteins (antigens). BCRs are formed through random somatic changes of germline DNA, creating a vast repertoire of unique sequences that enable …