1. Parkinson disease is a complex, age-related, neurodegenerative disease associated with dopamine deficiency and both motor and nonmotor deficits.
    Author: David K. Simon, Caroline M. Tanner, Patrik Brundin
    Publish Year: 2020

    Parkinson Disease Epidemiology, Pathology, Genetics, and ...

    pubmed.ncbi.nlm.nih.gov/31733690/
    pubmed.ncbi.nlm.nih.gov/31733690/
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  2. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov › books

    Parkinson’s Disease: Etiology, Neuropathology, and Pathogenesis

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  3. nih.gov
    https://pmc.ncbi.nlm.nih.gov › articles

    Parkinson Disease Epidemiology, Pathology, Genetics and …

    标记:
    Parkinson's disease
    Parkinson Disease Epidemiology
    Parkinson Disease Risk
  5. nih.gov
    https://pmc.ncbi.nlm.nih.gov › articles

    Parkinson’s Disease and Parkinsonism: Neuropathology …

    Parkinsonism is pathologically heterogeneous, with the most common pathologic substrates related to abnormalities in the presynaptic protein α-synuclein or the microtubule binding protein tau. In idiopathic Parkinson’s disease (PD), α …

  6. The Lancet
    https://www.thelancet.com › journals › lanc…

    The pathogenesis of Parkinson's disease - The Lancet

    2024年1月20日 · Parkinson's disease is a clinicopathological syndrome in which progressive asymmetric slowness of movement (bradykinesia), rigidity, tremor, and gait disturbance are associated with neuronal loss and the formation of α …

  7. Neuropathology
    https://neuropathology-web.org

    PARKINSON'S DISEASE - Neuropathology

    The key pathology in PD is α-synuclein accumulation. Large α-synuclein aggregates form round lamellated eosinophilic cytoplasmic inclusions, Lewy bodies (LBs), in the neuronal body, and fibrils, made of insoluble polymers of …

    标记:
    Parkinson's disease
    Pathology of PD
  8. PubMed
    https://pubmed.ncbi.nlm.nih.gov

    The pathogenesis of Parkinson's disease - PubMed

    标记:
    Parkinson's Disease Pubmed
    Pathology of Parkinson
  9. 其他用户还问了以下问题
    What is the pathogenesis of Parkinson's disease?
    Parkinson's disease is a progressive condition, and studies of disease pathogenesis encompass both the initiation of the disease and the development of progressively worsening clinical features, with the involvement of multiple brain regions.

    The pathogenesis of Parkinson's disease - The Lancet

    thelancet.com
    What are the underlying pathology of Parkinson's disease (PD)?
    But they are increasingly classified by underlying pathology (α-synucleinopathies, tauopathies, and TDP-43 proteinopathy). Parkinson’s disease (PD) is a progressive neurological disorder defined by a characteristic clinical syndrome by bradykinesia, tremor, rigidity, and postural instability.

    Parkinson’s Disease and Parkinsonism: Neuropathology - PMC

    pmc.ncbi.nlm.nih.gov
    Is Parkinson's disease a neurodegenerative disease?
    Parkinson’s disease (PD) is a complex progressive neurodegenerative disease characterized by tremor, rigidity, and bradykinesia, with postural instability appearing in some patients as the disease progresses.

    Parkinson’s Disease: Etiology, Neuropathology, and Pathogenesis

    ncbi.nlm.nih.gov
    What is Parkinson's disease (PD)?
    Parkinson’s disease (PD) is a progressive neurological disorder defined by a characteristic clinical syndrome by bradykinesia, tremor, rigidity, and postural instability. There are a large number of different disorders that can have some or all of these clinical features, and the clinical syndrome is referred to as “parkinsonism.”

    Parkinson’s Disease and Parkinsonism: Neuropathology - PMC

    pmc.ncbi.nlm.nih.gov
    Is the immune system involved in Parkinson's disease pathology?
    The involvement of the immune system in the pathology of Parkinson's disease has been linked to an interaction between the peripheral and central nervous system immune response. Whether this involvement is due to an immune response being a cause or consequence of Parkinson's disease pathology is still a matter of debate.

    Pathology of Parkinson's Disease - an overview - ScienceDirect

    sciencedirect.com
    What are the clinical features of Parkinson's disease (PD)?
    Antonina Kouli, Kelli M. Torsney, and Wei-Li Kuan. Parkinson’s disease (PD) is a common neurodegenerative disorder. While a number of non-motor manifestations arise, the typical clinical features involve a movement disorder consisting of bradykinesia, resting tremor, and rigidity, with postural instability occurring at a later stage.

    Parkinson’s Disease: Etiology, Neuropathology, and Pathogenesis

    ncbi.nlm.nih.gov
    反馈
  10. National Center for Biotechnology Information
    https://www.ncbi.nlm.nih.gov › books

    Pathology - Parkinson’s Disease - NCBI Bookshelf

    标记:
    Parkinson's Disease Pubmed
    Published:2018/12/21
    Pathology of Parkinsons
  11. PubMed
    https://pubmed.ncbi.nlm.nih.gov

    Parkinson Disease Epidemiology, Pathology, Genetics, and ...

    标记:
    Parkinson's Disease Pubmed
    Parkinson Disease Epidemiology
    Publish Year:2020
  12. ScienceDirect
    https://www.sciencedirect.com › topics › medicine-and...

    Pathology of Parkinson's Disease - an overview - ScienceDirect

    标记:
    Parkinson's Disease
    Parkinsons Disease Assn
    Pathology of PD
    Pd Patho
  13. ScienceDirect
    https://www.sciencedirect.com › science › article › pii

    The pathogenesis of Parkinson's disease - ScienceDirect