Limb development: a paradigm of gene regulation - Nature
2017年2月6日 · In vertebrates, limb development is orchestrated along three different axes. The proximal–distal axis (from the shoulder to fingers), controlled by the apical ectodermal ridge …
A human embryonic limb cell atlas resolved in space and time
2023年12月6日 · Limb maturation continues in a proximal–distal manner, controlled by a complex system of temporally and spatially restricted gene expression programmes, in which small …
From genes to networks: The genetic control of leaf development
Proximal-distal polarity. Growth along the proximal–distal axis determines the length of the leaf. The two genes BLADE-ON-PETIOLE1 (BOP1) and BOP2, which both harbor a BTB/POZ …
Generating the Proximal-Distal Axis of the Limb
The proximal-distal axis is defined only after the induction of the apical ectodermal ridge by the underlying mesoderm. The limb bud elongates by means of the proliferation of the …
Establishing the pattern of the vertebrate limb | Development
2020年9月11日 · Vertebrate limb anatomy along the proximo-distal axis comprises an invariant pattern of stylopod (i.e. humerus), zeugopod (i.e. radius/ulna) and autopod (wrist/digits) (Fig. 1 …
Proximo-distal positional information encoded by an Fgf ... - Science
2020年6月3日 · We report a gradient of Meis homeodomain transcription factors along the mouse limb bud proximo-distal (PD) axis antiparallel to and shaped by the inhibitory action of distal …
jing Is Required for Wing Development and to Establish the …
2006年5月1日 · The establishment of the proximo-distal (PD) axis in the legs of Drosophila melanogaster requires the expression of a nested set of transcription factors that are activated …
Adaxial–abaxial polarity: The developmental basis of leaf shape ...
2013年11月26日 · A leaf is divided into distinct portions along the proximal–distal axis: a leaf base, a petiole, and a lamina, as well as each leaflet in the case of compound leaves. …
Proximal–distal axis formation in the Drosophila leg | Nature
1997年7月10日 · Limb development requires the formation of a proximal–distal axis perpendicular to the main anterior–posterior and dorsal–ventral body axes. The secreted signalling proteins …
Proximodistal axis formation in the Drosophila leg: subdivision …
1999年1月1日 · The developing legs of Drosophila are subdivided into proximal and distal domains by the activity of the homeodomain proteins Homothorax (Hth) and Distal-less (Dll). …