Repressor - Wikipedia
In molecular genetics, a repressor is a DNA-or RNA-binding protein that inhibits the expression of one or more genes by binding to the operator or associated silencers. A DNA-binding repressor blocks the attachment of RNA polymerase to the promoter, thus preventing transcription of the genes into messenger RNA.
Repressor - National Human Genome Research Institute
6 天之前 · A repressor, as related to genomics, is a protein that inhibits the expression of one or more genes. The repressor protein works by binding to the promoter region of the gene(s), which prevents the production of messenger RNA (mRNA).
Repressor Definition & Meaning - Merriam-Webster
The meaning of REPRESSOR is one that represses; especially : a protein that is determined by a regulatory gene, binds to a genetic operator, and inhibits the initiation of transcription of messenger RNA.
Repressor - an overview | ScienceDirect Topics
A repressor is a molecule that blocks the access of RNA polymerase to target promoters, thereby preventing gene expression. It can also alter the structure of a chromosome segment or stop the activity of RNA polymerase that is already in a preinitiation complex at a promoter.
Transcriptional Enhancers and Repressors - Biology LibreTexts
2024年11月23日 · repressor: any protein that binds to DNA and thus regulates the expression of genes by decreasing the rate of transcription; activator: any chemical or agent which regulates one or more genes by increasing the rate of transcription
Repressor - an overview | ScienceDirect Topics
The repressor is a 155kDa tetrameric protein that binds to three operator sites within the lac operon. Isopropyl-b-d-thiogalactoside (IPTG) binds to the repressor and allosterically reduces its affinity for the operators, inducing the synthesis of lac mRNA.
Repressor - (Honors Biology) - Vocab, Definition, Explanations
A repressor is a type of protein that inhibits gene expression by binding to specific DNA sequences, preventing the transcription of genes into RNA. By doing so, repressors play a crucial role in regulating cellular processes, ensuring that genes are expressed only when needed and helping maintain cellular homeostasis.
13.7: Repressors - Biology LibreTexts
2021年2月28日 · When tryptophan is present in the cell, two tryptophan molecules bind to the trp repressor, which changes shape to bind to the trp operator. Binding of the tryptophan–repressor complex at the operator physically prevents the RNA polymerase from binding, and transcribing the downstream genes.
Towards evolving a better repressor - PMC
The repressor is a 360 amino acid protein that has a modular structure. It contains an NH 2-terminal or ‘headpiece’ domain (∼60 residues) that binds specifically to operator DNA and a COOH-terminal ‘core’ domain that binds inducers. The monomeric repressor self-associates into a dimer of dimers, where a dimeric repressor molecule ...
Repressors - (General Biology I) - Vocab, Definition ... - Fiveable
These changes may enhance or diminish a repressor's ability to bind DNA or interact with other proteins, thereby affecting which genes are expressed. This adaptability is crucial for organisms to respond effectively to fluctuating conditions and maintain homeostasis.