Functions and Diseases of the Retinal Pigment Epithelium
Retinal pigment epithelium (RPE) is formed from a single layer of regular polygonal cells arranged at the outermost layer of the retina. The outer side of the RPE is connected to Bruch’s membrane and the choroid, while the inner side is connected to the outer segment of photoreceptor cells.
The Retinal Pigment Epithelium in Health and Disease - PMC
Retinal pigment epithelial cells (RPE) constitute a simple layer of cuboidal cells that are strategically situated behind the photoreceptor (PR) cells. The inconspicuousness of this monolayer contrasts sharply with its importance [1].
The retinal pigment epithelium: Functions and roles in ocular …
2024年11月1日 · The retinal pigment epithelium (RPE) between retinal photoreceptors and choroidal capillaries is a single layer of cells that are of critical importance to the eye. RPE cells are derived from the anterior neural plate of neuroectodermal origin.
The cell biology of the retinal pigment epithelium - PubMed
The retinal pigment epithelium (RPE), a monolayer of post-mitotic polarized epithelial cells, strategically situated between the photoreceptors and the choroid, is the primary caretaker of photoreceptor health and function.
The Retinal Pigment Epithelium - Webvision - NCBI Bookshelf
2011年1月26日 · Retinal pigment epithelial cells modulate lymphocyte function at the blood-retina barrier by autocrine PGE2 and membrane-bound mechanisms. Cell Immunol. 1993; 149 :315–30.
The Retinal Pigment Epithelium: Development, Injury Responses, …
Here, we discuss what is known about RPE formation during development in mammalian and non-mammalian vertebrates, we detail the processes by which RPE cells respond to injury, and we describe examples of RPE-to-retina and RPE-to …
Retinal Pigment Epithelium - an overview | ScienceDirect Topics
The retinal pigment epithelium (RPE) is a single monolayer of cells that resides between the light-sensitive photoreceptors and the fenestrated choriocapillaris. It performs specific functions in support of the photoreceptor cells, including the reisomerization of visual chromophore, and phagocytosis of photoreceptor outer segment (POS ...
The cell biology of the retinal pigment epithelium
2020年9月1日 · The retinal pigment epithelium (RPE), a monolayer of post-mitotic polarized epithelial cells, strategically situated between the photoreceptors and the choroid, is the primary caretaker of photoreceptor health and function.
The retinal pigment epithelium by Olaf Strauss – Webvision
At a first glance, light absorption is the most obvious function of the RPE. The cells are heavily pigmented and cover the inner surface of the bulbus. As in a camera, it improves the quality of the optical system of the eye by absorbing scattered light. For a long time this function was believed to be the only one by the RPE.
The role of the retinal pigment epithelium: Topographical
2001年5月1日 · The retinal pigment epithelium (RPE) is a single layer of post-mitotic cells, which functions both as a selective barrier to and a vegetative regulator of the overlying photoreceptor layer,...
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