Protein Homeostasis - an overview | ScienceDirect Topics
The term protein homeostasis describes an adequate balance of the ∼20,000 different protein species contained in the mammalian proteome to preserve cellular functions. 26–28 Cells …
Proteostasis - Wikipedia
The unfolded protein response in the endoplasmatic reticulum (ER) is activated by imbalances of unfolded proteins inside the ER and the proteins mediating protein homeostasis. Different …
Protein Homeostasis - an overview | ScienceDirect Topics
Protein homeostasis (proteostasis) refers to an extensive network of components that acts to maintain proteins in the correct concentration, conformation, and subcellular location, to …
Protein homeostasis networks in physiology and disease - PMC
This protein homeostasis network involves families of folding catalysts, co-factors under specific environmental and metabolic conditions. Maintaining protein homeostasis is particularly …
Protein homeostasis from the outside in - Nature Cell Biology
2020年7月8日 · Secretory proteins undergo multiple rounds of co- and post-translational quality control checks inside the cell, but how their integrity is maintained outside the cell is an …
Protein Homeostasis - Bristol Myers Squibb
Q: What is protein homeostasis? A: Protein homeostasis is a field of study dedicated to maintaining the equilibrium of proteins in the human body. Proteins are important, complex …
The Biology of Proteostasis in Aging and Disease - PMC
Loss of protein homeostasis (proteostasis) is a common feature of aging and disease that is characterized by the appearance of nonnative protein aggregates in various tissues. Protein …
线粒体与细胞蛋白质稳态 - pku.edu.cn
正细胞蛋白质稳态(protein homeostasis or proteostasis)是指细胞内蛋白质的分子合成、结构与功能成熟、蛋白质量控制(protein quality control)、折叠修饰、定位转运、功能恢复、降解等复杂过 …
Organismal Protein Homeostasis Mechanisms - PubMed
Proteostasis is achieved via a conserved network of quality control pathways that orchestrate the biogenesis of correctly folded proteins, prevent proteins from misfolding, and remove …
Protein Homeostasis, Second Edition - cshperspectives.cshlp.org
Protein homeostasis, or proteostasis, refers to the concept that there are a variety of highly interactive pathways within cells that control the entire life cycle of the proteome and its …
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